Study identifies interaction site for serotonin type 3A and RIC-3 chaperone

(Texas Tech University Health Sciences Center) Serotonin type 3A is a member of the protein superfamily known as pentameric ligand-gated ion channels. When these channels don't function properly, these proteins have been linked to Alzheimer's disease, Parkinson's disease, epilepsy, schizophrenia, alcohol addiction and myasthenia gravis. Michaela Jansen, Pharm.D., Ph.D., from the Texas Tech University Health Sciences Center recently completed a study that provides novel insights into a protein-pr...